Ricardo A. Verdugo

Ricardo VerdugoFormer Postdoctoral Associate
Churchill Group, The Jackson Laboratory


Address:

The Jackson Laboratory
600 Main Street
Bar Harbor
Maine, 04609

Phone: 207-288-6715
Email: ricardo.verdugo@jax.org

Research Projects in The Churchill Group:

Genome-Wide (GW) Gene Expression Survey in 17 Tissues
Illumina Mouse-6 experiment on normal animals for adrenals, brown adipose tissue, brain, colon, duodenum, heart, ileum, jejunum, kidney, liver, lung, muscle, pancreas, spleen, stomach, testis, and white adipose tissue. Replication: 5 animals/tissue. Objectives: (1) to generate a resource to complement the GNF Gene Atlas, (2) to identify novel genomic regulators of gene expression.

GW Gene Expression Survey in 26 Mouse Strains
Illumina Mouse-6 experiment on right and left kidneys, liver and spleen on normal animals. Replication: 5 animals/sex/tissue.

Genetical Genomics experiment in a MRL/MpJ x SM/J F2 cross
Affymetrix experiment on liver, gonadal fat and kidneys in 144 males and 136 females from a 363 F2 population. Three males and females also profiled from both parental and F1 populations. Objective: dissection of genetic architecture and gene interactions underlying the determination of HDL level.

Selected Publications:

Importance of randomization in microarray experimental designs with Illumina platforms
Verdugo RA, Deschepper CF, Muñoz G, Pomp D, Churchill GA.
Nucleic Acids Res. 2009 Sep;37(17):5610-8. PMCID: PMC2761262. [ PDF ]

Comparison of Gene Coverage of Mouse Oligonucleotide Microarray Platforms.
Verdugo RA, Medrano JF.
BMC Genomics. 2006 Mar 21;7:58. [ PDF ]

Presentations:

Automation and self-documentation of analysis workflows for high-throughput data
Ricardo A. Verdugo and Gary A. Churchill.
9th Annual Meeting of the Complex Trait Community. Chicago, IL. May 7-10, 2010. Live demo.

A survey of gene expression in 17 mouse tissues with biological replication (PDF)
Ricardo A. Verdugo, Peter T. Vedell, Joel H. Graber, Beverly Paigen, and Gary A. Churchill.
9th Annual Meeting of the Complex Trait Community. Chicago, IL. May 7-10, 2010. Poster.

Importance of Randomization in Microarray Experimental Designs with Illumina Platforms (PDF)
Ricardo A Verdugo
, Christian F Deschepper, and Gary A Churchill
8th Annual Meeting of the Complex Trait Community in Manchester, UK, May 2 - 5, 2009. Poster