Overexpression of innate immune response genes in a model of recessive polycystic kidney disease

Description

Defects in the primary cilium/basal body complex of renal tubular cells cause polycystic kidney disease (PKD). To uncover pathways associated with disease progression, kidney transcriptome of 10-day-old severely and mildly affected cpk mice, a model of recessive PKD, were examined using Affymetrix GeneChips

Reference

Mrug M, Zhou J, Woo Y, Cui X, Szalai AJ, Novak J, Churchill GA, Guay-Woodford LM.
Overexpression of innate immune response genes in a model of recessive polycystic kidney disease
Kidney Int. 2008 Jan;73(1):63-76.

Datasets


README file: readme.txt

Design file: design.dat

CEL files:
1M Mouse430_2.CEL
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2M Mouse430_2.CEL
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