Phenotype

Datasets Available to Download ( alphabetical order by first author )

Genetic analysis of complex traits in the emerging collaborative cross – white spot, body weight and liver gene expression

Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, Pardo-Manuel de Villena F, Churchill GA.
Genetic analysis of complex traits in the emerging collaborative cross
Genome Res. 2011 Aug;21(8):1223-38. PMCID: PMC3149489 [ Full Text ] [ Highlight in Nature Reviews Genetics ]

Genetic analysis of hematological parameters in incipient lines of the Collaborative Cross

Kelada SNP, Aylor DL, Peck BCE, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, Pardo-Manuel de Villena F, Collins FS.
Genetic Analysis of Hematologic Parameters in Incipient Lines of the Collaborative Cross
G3 (Bethesda). 2012 Feb;2(2):157-65. PMCID: PMC3284323 [ Full Text ]

Eight-strain diallel from establishment of Collaborative Cross - Blood composition, blood pressure, plasma chemistries, electrocardiography, densiometry and body composition

Lenarcic AB, Svenson KL, Churchill GA, Valdar W.
A General Bayesian Approach to Analyzing Diallel Crosses of Inbred Strains
Genetics. 2012 Feb;190(2):413-35. PMCID: PMC3276624 [ Full Text ] [ software ]

Relationships of dietary fat, body composition, and bone mineral density

Li R, Svenson KL, Donahue LR, Peters LL, Churchill GA.
Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels
Physiol Genomics. 2008 Mar 14;33(1):26-32. [ Full Text ]

Body composition and bone density data from SM x NZB and NZB x RF mouse intercross populations

Li R, Tsaih SW, Shockley K, Stylianou IM, Wergedal J, Paigen B, Churchill GA.
Structural model analysis of multiple quantitative traits
PLoS Genet. 2006 Jul;2(7):e114. PMCID: PMC1513264. [ Full Text ]

Architecture of energy balance traits in emerging lines of the Collaborative Cross – 15 metabolism- and exercise-related phenotypes

Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, Pardo Manuel de Villena F, Threadgill DW, Pomp D.
Architecture of energy balance traits in emerging lines of the Collaborative Cross
Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1124-34. PMCID: PMC3118585 [Available on 2012/6/1]

Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations

Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations
Nadeau JH, Burrage LC, Restivo J, Pao YH, Churchill G, Hoit BD.
Genome Res. 2003 Sep;13(9):2082-91. PMCID: PMC403692. [ Full Text ]

Diversity Outcross (DO) QTL Mapping data - high fat diet, multiple phenotypes

Churchill GA, Gatti DM, Munger SC, Svenson KL
The Diversity Outbred Mouse Population
Mammalian Genome 2012 Oct;23(9-10):713-8.

Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA.
High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population
Genetics. 2012 Feb;190(2):437-47. PMCID: PMC3276626 [Available on 2013/2/1]

Multiple trait measurements in 43 inbred mouse strains

Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL.
Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations
J Appl Physiol. 2007 Jun;102(6):2369-78. [ Full Text ]

Genome-wide association mapping of quantitative traits in NMRI outbred mice

Genome-Wide Association Mapping of Quantitative Traits in Outbred Mice
Zhang W, Korstanje R, Thaisz J, Staedtler F, Harttman N, Xu L, Feng M, Yanas L, Yang H, Valdar W, Churchill GA, DiPetrillo K.
G3 (Bethesda). 2012 Feb;2(2):167-74. PMCID: PMC3284324 [ Full Text ]